Scanning electron micrograph of a Drosophila melanogaster sestrin-null mutant. Sestrin-null Drosophila are used to study pathways involved in oxidative stress and aging. Relevant article: Lee, JH ...

Gallbladder wall of a human patient with gallstones. The duct (clear zone at center) is lined by highly polarized epithelial cells with dark nuclei at the base. At the top of the picture, below the...

Gallbladder wall of a human patient with gallstones. The top layer is composed of highly polarized epithelial cells with microvilli partially visible at the apex and dark nuclei at the base. Below ...

Gallbladder wall of a human patient with gallstones. This low magnification view shows the wall of the diseased gallbladder to have a top layer of highly polarized epithelial cells over a large volu...

The JNK phosphatase puckered, whose expression can be reported via a lacZ enhancer trap, is expressed in very low levels in uninjured neurons; however, nerve crush induces a dramatic increase in puc-l...

Adhesive capture and dispersal of a cluster of blood cells at a Drosophila third-instar larval wound site. Time-lapse movie of blood cells visualized from the dorsal side of a Nrg-GFP;PxnYFP larva. A ...

The JNK phosphatase puckered, whose expression can be reported via a lacZ enhancer trap, is expressed in very low levels in uninjured neurons; however, nerve crush induces a dramatic increase in puc-l...

The JNK phosphatase puckered, whose expression can be reported via a lacZ enhancer trap, is expressed in very low levels in uninjured neurons; however, nerve crush induces a dramatic increase in puc-l...

The JNK phosphatase puckered, whose expression can be reported via a lacZ enhancer trap, is expressed in very low levels in uninjured neurons; however, nerve crush induces a dramatic increase in puc-l...

PrA contains a distinct determinant for glycan-independent ERAD (ER associated degradation). A mutant of the vacuolar proteinase A (PrA*-Gldelta4) (green) is a substrate of ER quality control (ERQC) m...